Chemical Synthesis, Formulation, & Workup Development

LOCATION: Canada

Air Sensitive Specialty Chemical Protocol Optimization

Client Objective

AGEIAS’ client was developing a process to produce a specialty chemical for battery applications. The process chemistry is challenging: it is air- and moisture- sensitive; requires toxic gaseous reagents; and has high product purity targets. The client requested AGEIAS’s collaboration in developing and optimizing synthesis and workup protocols to meet scale and purity requirements for initial customer validation.

The AGEIAS Approach

Developing a scalable synthesis protocol while meeting stringent purity requirements requires extensive lab trials to identify the cause of deficiencies and test proposed solutions. To supplement the client’s own trial work, AGEIAS designed and built an in-house Schlenk line based set up with engineered safety monitoring and protocols. The setup was able to run accelerated trials while effectively managing hazards associated with toxic gaseous reagents and air- and moisture-sensitive chemistry.

Customer Value

AGEIAS was able to accelerate development work by conducting additional lab trials at multiple scales under safe and controlled conditions. The experimental results were used for troubleshooting process challenges to ultimately develop a protocol for larger lab scales that meet market-based purity specifications for customer validation. The insight gained allowed AGEIAS to begin scaling up their client’s process from lab to pilot.

Capabilities Demonstrated

Air- and moisture- sensitive chemistry
Toxic reagent handling
Laboratory process development and scale-up
Experimental design and process optimization
Reaction synthesis and workup development
Product isolation and purification

How We Help You:

Process development starts in the lab and requires systematic experimentation and optimization. AGEIAS has the expertise and infrastructure to work collaboratively with you to accelerate the development of synthesis, workup, and isolation protocols for even the most challenging chemistries.